The Catholic University of America

 

Xiaolong Luo, Ph.D.

Associate Professor

Mechanical Engineering 

G37 Pangborn Hall
202-319-6952 Phone
202-319-5173 Fax 
luox@cua.edu

Education

B.E., Mechatronics, Zhejiang University, 2001
M.S., Mechanical Engineering, Temple University, 2003
Ph.D., Bioengineering, University of Maryland, 2008

Biography in Brief

Xiaolong Luo joined the faculty of the School of Engineering’s Department of Mechanical Engineering as an Assistant Professor in January 2013, and was promoted to be Associate Professor in August 2017. His research handles fluids in microscale (microfluidics), fabricates microscale devices and systems (microfabrication, MEMS), and integrates biology into devices (biofabrication, bioMEMS). Dr. Luo found and directs the Integrated BioMicroFluidics (iBMF) laboratory, and works with biopolymers extracted from crab/insect shells (chitosan) and sea weed algae (alginate) to construct 3D hydrogels and membranes, assemble biomolecules and living cells, and entrap optically-active nanoparticles in microfluidic networks with spatial and temporal programmability. Dr. Luo actively collaborates with biologists, engineers and chemists, and develops novel Lab-on-a-Chip devices that find important applications in protein/metabolic engineering, cellular and molecular biology, in situ biosensing and tissue engineering in microenvironments, which help to expedite novel drug discovery and improve human health. Dr. Luo is the recipient of the Burns Junior Faculty Fellowship award from the School of Engineering at CUA in 2013, the CAREER award from National Science Foundation (NSF) in 2016, the Kaman Excellence in Research Award from the School of Engineering at CUA in 2016, and the Young Faculty Scholar’s Award at CUA in 2017.  

Recent Publications

1.     A. Alshehri, O. C. Wilson, B. R. Dahal, J. Philip, X. Luo and C. B. Raub, “Magnetic nanoparticle-loaded alginate beads for local microactuation of in vitro tissue constructs”, Colloids and Surfaces B: Biointerfaces, 2017, In press.

2.     W. Shang, C. Tsao, X. Luo, M. Teodoro, R. McKay, D. Quan, H. Wu, G. F. Payne and W. E. Bentley, “A simple and reusable bilayer microfluidic device for the studies of bacterial gradient-sensing behaviors”, Biomicrofluidics, 2017, 11, 044114, 1-10.

3.     K. Li, S. O. Correa, P. Pham, C. Raub and X. Luo, “Birefringence microscopy revealing crystalline gelation mechanism of biofabricated chitosan membranes in microfluidics”, Biofabrication, 2017, 9, 034101.

4.     P. Pham, T. Vo and X. Luo, “Steering air bubbles with an add-on vacuum layer for biopolymer membranes biofabrication in PDMS microfluidics”, Lab on a Chip, 2017, 17, 248-255.

5.     H. C. Wu, D. N. Quan, C. Y. Tsao, Y. Liu, J. L. Terrell, X. Luo, J. C. Yang, G. F. Payne and W. E. Bentley, “Conferring biological activity to native spider silk: A biofunctionalized protein-based microfiber”, Biotechnology & Bioengineering, 2017, 114, 83-95.

6.     C. J. Wolfram, G. W. Rubloff and X. Luo, “Perspectives in Flow-Based Microfluidic Gradient Generators for Characterizing Bacterial Chemotaxis”, Biomicrofluidics, 2016, 10, 061301, 1-12. 

7.     X. Luo, T. Vo, F. Jambi, P. Pham and J. Choy, “Microfluidic partition with in situ biofabricated semipermeable biopolymer membranes for static gradient generation”, Lab on a Chip, 2016, 3815-3823.

8.     X. Luo, C. Y. Tsao, H. C. Wu, D. N. Quan, G. F. Payne, G. W. Rubloff and W. E. Bentley, “Distal modulation of cell-cell signaling in a synthetic ecosystem in partitioned microfluidics”, Lab on a Chip, 2015, 8:1842-51.

9.     X. Luo, H. C. Wu, J. Betz, W. E. Bentley and G. W. Rubloff, “Air bubble-initiated biofabrication of freestanding, semi-permeable biopolymer membranes in PDMS microfluidics”, Biochemical Engineering Journal, 2014, 89, 2-9.

10.  J. F. Betz, Y. Cheng, C. Y. Tsao, A. Zargar, H. C. Wu, X. Luo, G. F. Payne, W. E. Bentley and G. W. Rubloff, “Optically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces”, Lab on a Chip, 2013, 10, 1854-1858.

11.  T. Gordonov, B. Liba, J. L. Terrell, Y. Cheng, X. L. Luo, G. F. Payne and W. E. Bentley, “Bridging the Bio-Electronic Interface with Biofabrication”, Journal of Visualized Experiments, 2012, 64, e4231.

12.  X. L. Luo, “Biofabrication in microfluidics: a converging fabrication paradigm to exploit biology in microsystems”, Journal of Bioengineering & Biomedical Science, 2012, 2:e104.

13.   X. L. Luo, H. C. Wu, C. Y. Tsao, Y. Cheng, J. Betz, G. F. Payne, G. W. Rubloff and W. E. Bentley, “Biofabrication of stratified biofilm mimics for observation and control of bacterial signaling”, Biomaterials, 2012, 33, 5136-5143.

14.  Y. Cheng, X. L. Luo, G. F. Payne and G. W. Rubloff, “Biofabrication: Programmable Assembly of Hydrogels in Microfluidics as Scaffolds for Biology”, Journal of Materials Chemistry, 2012, 22, 7659-7666.

15.  J. L. Terrell1, T. Gordonov, Y. Cheng, H. C. Wu, D. Sampey, X. L. Luo, C. Y. Tsao, R. Ghodssi, G. W. Rubloff, G. F. Payne and W. E. Bentley, “Integrated Biofabrication for Electro-addressed In-Film Bioprocessing”, Biotechnology Journal, 2012, 7, 428-439.

 

16.  Y. Cheng, C. Y. Tsao, H. C. Wu, X. L. Luo, J. L. Terrell, J. Betz, G. F. Payne, W. Bentley and G. W. Rubloff, “Electroaddressing functionalized polysaccharides as model biofilms for interrogating cell signaling”, Advanced Functional Materials, 2012, 22, 519-528. 

Website

http://faculty.cua.edu/luox